Mouse Ibtk activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ibtk
Locus ID	108837
Kit Components	GA212150G1, Ibtk gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212150G2, Ibtk gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212150G3, Ibtk gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081282, NM_175371
Synonyms	5430411K16Rik; AA409502; BTKI; mKIAA1417
Summary	Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription (By similarity).[UniProtKB/Swiss-Prot Function]

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