Mouse Epsti1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Epsti1
Locus ID	108670
Kit Components	GA212122G1, Epsti1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212122G2, Epsti1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212122G3, Epsti1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029495, NM_178825
Synonyms	2310046K10Rik; 5033415K03Rik; BRESI1
Summary	Plays a role in M1 macrophage polarization and is required for the proper regulation of gene expression during M1 versus M2 macrophage differentiation (PubMed:29217193). Might play a role in RELA/p65 and STAT1 phosphorylation and nuclear localization upon activation of macrophages (PubMed:29217193).[UniProtKB/Swiss-Prot Function]

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