Mouse Mthfd1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mthfd1
Locus ID	108156
Kit Components	GA212107G1, Mthfd1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212107G2, Mthfd1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212107G3, Mthfd1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_138745
Synonyms	Dcs; E430024A07Rik; Mthfd
Summary	This gene encodes a trifunctional cytoplasmic enzyme. The encoded protein functions as a methylenetetrahydrofolate dehydrogenase, a methenyltetrahydrofolate cyclohydrolase, and a formyltetrahydrofolate synthase. The encoded enzyme functions in de novo synthesis of purines and thymidylate and in regeneration of methionine from homocysteine. [provided by RefSeq, Oct 2009]

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