Mouse Fermt3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fermt3
Locus ID	108101
Kit Components	GA212090G1, Fermt3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212090G2, Fermt3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212090G3, Fermt3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_153795, NM_001362399
Synonyms	C79673; Kindlin3
Summary	Plays a central role in cell adhesion in hematopoietic cells (By similarity). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (PubMed:18278053). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234461). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (PubMed:18278053).[UniProtKB/Swiss-Prot Function]

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