Mouse Grm5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Grm5
Locus ID	108071
Kit Components	GA212078G1, Grm5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212078G2, Grm5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212078G3, Grm5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081414, NM_001143834, NM_001033224
Synonyms	6430542K11Rik; AI850523; Glu5R; Gprc1e; mGluR5; mGluR5b
Summary	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).[UniProtKB/Swiss-Prot Function]

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