Mouse Mthfs activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mthfs
Locus ID	107885
Kit Components	GA212047G1, Mthfs gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA212047G2, Mthfs gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA212047G3, Mthfs gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026829, NM_001359993
Synonyms	1110034I12Rik; 2310020H23Rik; AI119695
Summary	Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5-formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10-methenyltetrahydrofolate (By similarity).[UniProtKB/Swiss-Prot Function]

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