Mouse Pdzd8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pdzd8
Locus ID	107368
Kit Components	GA211988G1, Pdzd8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211988G2, Pdzd8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211988G3, Pdzd8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033222
Synonyms	A630041P07Rik; AV329468; AW228944; Pdzk8
Summary	Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes (PubMed:29097544). PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering is essential for endoplasmic reticulum-mitochondria Ca(2+) transfer (PubMed:29097544). In neurons, involved in the regulation of dendritic Ca(2+) dynamics by regulating mitochondrial Ca(2+) uptake in neurons (PubMed:29097544).[UniProtKB/Swiss-Prot Function]

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