Mouse Ift140 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ift140
Locus ID	106633
Kit Components	GA211942G1, Ift140 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211942G2, Ift140 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211942G3, Ift140 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_134126
Synonyms	AI661311; mKIAA0590; Tce5; Wdtc2
Summary	Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport and entry into cilia of G protein-coupled receptors (GPCRs) (By similarity). Plays a pivotal role in proper development and function of ciliated cells through its role in ciliogenesis and/or cilium maintenance (PubMed:22282595). Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells (PubMed:24619649).[UniProtKB/Swiss-Prot Function]

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