Mouse Ccdc65 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ccdc65
Locus ID	105833
Kit Components	GA211896G1, Ccdc65 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211896G2, Ccdc65 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211896G3, Ccdc65 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_153518, NM_001364844
Synonyms	4933417K04Rik; AI428139; AU020178; NYD-SP28
Summary	Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.[UniProtKB/Swiss-Prot Function]

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