Mouse Ptpn23 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ptpn23
Locus ID	104831
Kit Components	GA211838G1, Ptpn23 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211838G2, Ptpn23 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211838G3, Ptpn23 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081043
Synonyms	AI462446; PTP-TD14
Summary	Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis (By similarity).[UniProtKB/Swiss-Prot Function]

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