Mouse Pik3r6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pik3r6
Locus ID	104709
Kit Components	GA211829G1, Pik3r6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211829G2, Pik3r6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211829G3, Pik3r6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001004435, NM_001081566, NR_126153, NR_126154
Synonyms	BB220380; p84; p84 PIKAP; p87(PIKAP); p87PIKAP
Summary	Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 11. The protein binds to both the catalytic subunit and to G beta-gamma, and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]

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