Mouse Qsox1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Qsox1
Locus ID	104009
Kit Components	GA211777G1, Qsox1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211777G2, Qsox1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211777G3, Qsox1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001024945, NM_023268
Synonyms	1300003H02Rik; Qscn6; QSOX; SOx
Summary	Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide (PubMed:26819240). Plays a role in disulfide bond formation in a variety of extracellular proteins (PubMed:26819240). In fibroblasts, required for normal incorporation of laminin into the extracellular matrix, and thereby for normal cell-cell adhesion and cell migration (PubMed:26819240).[UniProtKB/Swiss-Prot Function]

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