Mouse Tmem98 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmem98
Locus ID	103743
Kit Components	GA211761G1, Tmem98 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211761G2, Tmem98 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211761G3, Tmem98 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029537
Synonyms	6530411B15Rik; AI463522
Summary	Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation (PubMed:25946230). The secreted form promotes differentiation of T helper 1 cells (Th1) (PubMed:25946230).[UniProtKB/Swiss-Prot Function]

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