Mouse Mgat4b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mgat4b
Locus ID	103534
Kit Components	GA211749G1, Mgat4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211749G2, Mgat4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211749G3, Mgat4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145926
Synonyms	AA407995; GnTIVb
Summary	Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis (By similarity).[UniProtKB/Swiss-Prot Function]

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