Mouse Dohh activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dohh
Locus ID	102115
Kit Components	GA211688G1, Dohh gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211688G2, Dohh gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211688G3, Dohh gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_133964
Synonyms	1110033C18Rik; AI585913; AL022869; Hlrc1
Summary	Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate produced by deoxyhypusine synthase/DHPS on a critical lysine of the eukaryotic translation initiation factor 5A/eIF-5A. This is the second step of the post-translational modification of that lysine into an unusual amino acid residue named hypusine. Hypusination is unique to mature eIF-5A factor and is essential for its function.[UniProtKB/Swiss-Prot Function]

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