Mouse Spty2d1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Spty2d1
Locus ID	101685
Kit Components	GA211663G1, Spty2d1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211663G2, Spty2d1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211663G3, Spty2d1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175318
Synonyms	5830435K17Rik; AI852426; P16H6
Summary	Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin. Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription. Binds DNA and histones and promotes nucleosome assembly (in vitro). Facilitates formation of tetrameric histone complexes containing histone H3 and H4 (By similarity). Modulates RNA polymerase 1-mediated transcription (By similarity). Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holliday junction DNA (By similarity).[UniProtKB/Swiss-Prot Function]

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