Mouse Plekhg2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Plekhg2
Locus ID	101497
Kit Components	GA211651G1, Plekhg2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211651G2, Plekhg2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211651G3, Plekhg2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001083912, NM_001290542, NM_138752
Synonyms	AI194308; Clg; Cslg
Summary	May be a transforming oncogene with exchange activity for CDC42. May be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42 (PubMed:11839748). Activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein) (By similarity). Involved in the regulation of actin polymerization (By similarity).[UniProtKB/Swiss-Prot Function]

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