Mouse Obsl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Obsl1
Locus ID	98733
Kit Components	GA211520G1, Obsl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211520G2, Obsl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211520G3, Obsl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001310679, NM_178884
Synonyms	AW822216
Summary	Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Acts as a regulator of the Cul7-RING(FBXW8) ubiquitin-protein ligase, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain. Required to localize CUL7 to the Golgi apparatus in neurons (By similarity).[UniProtKB/Swiss-Prot Function]

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