Mouse Slc9b2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc9b2
Locus ID	97086
Kit Components	GA211464G1, Slc9b2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211464G2, Slc9b2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211464G3, Slc9b2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_178877
Synonyms	C80638; nha-oc; NHA2; nhaoc; NHE10; Nhedc2
Summary	Na(+)/H(+) antiporter that extrudes Na(+) or Li(+) in exchange for external protons across the membrane (PubMed:18508966, PubMed:17988971). Contributes to the regulation of intracellular pH, sodium homeostasis, and cell volume. Plays an important role for insulin secretion and clathrin-mediated endocytosis in beta-cells (PubMed:23720317). Involved in sperm motility and fertility (PubMed:27010853). It is controversial whether SLC9B2 plays a role in osteoclast differentiation (PubMed:17988971) or not (PubMed:20441802, PubMed:22985540).[UniProtKB/Swiss-Prot Function]

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