Mouse Gopc activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gopc
Locus ID	94221
Kit Components	GA211433G1, Gopc gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211433G2, Gopc gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211433G3, Gopc gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199272, NM_053187
Synonyms	2210402P09Rik; AI844555; CAL; FIG; GOPC1; PIST
Summary	Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.[UniProtKB/Swiss-Prot Function]

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