Mouse Pla1a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pla1a
Locus ID	85031
Kit Components	GA211297G1, Pla1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211297G2, Pla1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211297G3, Pla1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_134102
Synonyms	AA986889; Ps-pla1; Pspla1
Summary	Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production (By similarity).[UniProtKB/Swiss-Prot Function]

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