Mouse Jam3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Jam3
Locus ID	83964
Kit Components	GA211270G1, Jam3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211270G2, Jam3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211270G3, Jam3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_023277
Synonyms	1110002N23Rik; JAM-3; JAM-C; Jcam3
Summary	Mediates cell-cell adhesion. Functions as counter-receptor for JAM2 (PubMed:15372036). Functions as a counter-receptor for ITGAM, mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN) (By similarity). Plays a role in angiogenesis (PubMed:15994945). May play a role in the regulation of cell migration (By similarity). Required for normal polarization and acrosome formation in developing spermatids, and for normal male fertility (PubMed:15372036).[UniProtKB/Swiss-Prot Function]

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