Mouse Cenpq activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cenpq
Locus ID	83815
Kit Components	GA211261G1, Cenpq gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211261G2, Cenpq gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211261G3, Cenpq gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_031863
Synonyms	2610528M18Rik
Summary	Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores.[UniProtKB/Swiss-Prot Function]

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