Mouse Smarcd2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Smarcd2
Locus ID	83796
Kit Components	GA211258G1, Smarcd2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211258G2, Smarcd2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211258G3, Smarcd2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001130187, NM_031878
Synonyms	AW322457; Baf60b
Summary	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Critical regulator of myeloid differentiation, controlling granulocytopoiesis and the expression of genes involved in neutrophil granule formation.[UniProtKB/Swiss-Prot Function]

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