Mouse Jdp2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Jdp2
Locus ID	81703
Kit Components	GA211191G1, Jdp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211191G2, Jdp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211191G3, Jdp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001205052, NM_001205053, NM_030887
Synonyms	Jundm2; Jundp2; TIF
Summary	Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1, such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin (By similarity).[UniProtKB/Swiss-Prot Function]

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