Mouse Spz1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Spz1
Locus ID	79401
Kit Components	GA211095G1, Spz1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211095G2, Spz1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211095G3, Spz1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_030237
Synonyms	1700027M20Rik; AI429130
Summary	Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. Directly binds to a guanine-rich region of the PCNA promoter and up-regulates its expression which in turn induces cell transformation and tumor formation. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis.[UniProtKB/Swiss-Prot Function]

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