Mouse Misp activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Misp
Locus ID	78906
Kit Components	GA211065G1, Misp gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211065G2, Misp gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211065G3, Misp gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_030218
Synonyms	9130017N09Rik
Summary	Plays a role in mitotic spindle orientation and mitotic progression. Regulates the distribution of dynactin at the cell cortex in a PLK1-dependent manner, thus stabilizing cortical and astral microtubule attachments required for proper mitotic spindle positioning. May link microtubules to the actin cytoskeleton and focal adhesions. May be required for directed cell migration and centrosome orientation. May also be necessary for proper stacking of the Golgi apparatus (By similarity).[UniProtKB/Swiss-Prot Function]

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