Mouse Celf3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Celf3
Locus ID	78784
Kit Components	GA211034G1, Celf3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA211034G2, Celf3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA211034G3, Celf3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289613, NM_001289616, NM_001289620, NM_172434, NR_110353, NM_001357784, NM_001357785, NM_001357786, NM_001357787, NR_151857
Synonyms	4930415M08Rik; BRUNOL1; CAGH4; ERDA4; Tnrc4
Summary	RNA-binding protein involved in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA (By similarity).[UniProtKB/Swiss-Prot Function]

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