Mouse Rbsn activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rbsn
Locus ID	78287
Kit Components	GA210932G1, Rbsn gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210932G2, Rbsn gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210932G3, Rbsn gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_030081
Synonyms	5330426D11Rik; Zfyve20
Summary	Rab4/Rab5 effector protein acting in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Required for endosome fusion either homotypically or with clathrin coated vesicles. Plays a role in the lysosomal trafficking of CTSD/cathepsin D from the Golgi to lysosomes. Also promotes the recycling of transferrin directly from early endosomes to the plasma membrane. Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate (PtdInsP3). Plays a role in the recycling of transferrin receptor to the plasma membrane (By similarity).[UniProtKB/Swiss-Prot Function]

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