Mouse Sbf1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Sbf1
Locus ID	77980
Kit Components	GA210854G1, Sbf1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210854G2, Sbf1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210854G3, Sbf1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081030, NM_001170561, NM_030019
Synonyms	2610510A08Rik; B230113C15Rik; mKIAA3020; Mtmr5
Summary	Acts as an adapter for the phosphatase MTMR2 to regulate MTMR2 catalytic activity and subcellular location. May function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts.[UniProtKB/Swiss-Prot Function]

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