Mouse Rnf170 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rnf170
Locus ID	77733
Kit Components	GA210812G1, Rnf170 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210812G2, Rnf170 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210812G3, Rnf170 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029965, NM_001357292, NM_001357293, NM_001357294, NM_001357295, NR_151666, NR_151667
Synonyms	6720407G21Rik; AI481227
Summary	E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells.[UniProtKB/Swiss-Prot Function]

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