Mouse Slc9a8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc9a8
Locus ID	77031
Kit Components	GA210687G1, Slc9a8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210687G2, Slc9a8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210687G3, Slc9a8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_148929, NM_178371, NR_130767
Synonyms	1200006P13Rik; 6430709P13Rik; AI182282; NHE-8; NHE8
Summary	This gene encodes a member of the Na+/H+ exchanger (NHE) family of integral membrane transporter proteins. The encoded protein is expressed on the apical membrane of the intestinal epithelial cells and plays an important role in mucosal protection. Loss of the encoded protein in mice results in a decrease in the number of goblet and mucin-positive cells, disorganization of the mucin layer, and a decrease in mucosal pH in the colon. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2015]

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