Mouse Ifi27l2a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ifi27l2a
Locus ID	76933
Kit Components	GA210659G1, Ifi27l2a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210659G2, Ifi27l2a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210659G3, Ifi27l2a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001281830, NM_029803
Synonyms	2310061N23Rik; Ifi27; Isg12; Isg12(b1)
Summary	May be involved in the interferon-induced negative regulation of the transcriptional activity of NR4A1, NR4A2 and NR4A3 through the enhancement of XPO1-mediated nuclear export of these nuclear receptors (PubMed:22427340). Through the regulation of NR4A1 transcriptional activity, may play a role in the vascular response to injury (PubMed:22427340).[UniProtKB/Swiss-Prot Function]

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