Mouse Cyfip2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cyfip2
Locus ID	76884
Kit Components	GA210643G1, Cyfip2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210643G2, Cyfip2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210643G3, Cyfip2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001252459, NM_001252460, NM_133769
Synonyms	1500004I01Rik; 6430511D02Rik; AA930218; AU022376; mKIAA1168; Pir121
Summary	Part of the WAVE1 complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). Involved in T-cell adhesion and p53-dependent induction of apoptosis (By similarity). Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).[UniProtKB/Swiss-Prot Function]

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