Mouse Dcun1d5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dcun1d5
Locus ID	76863
Kit Components	GA210637G1, Dcun1d5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210637G2, Dcun1d5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210637G3, Dcun1d5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029775, NM_001357483, NM_001357484
Synonyms	3110001A18Rik; 4833420K19Rik; AW060460; D430047L21Rik
Summary	Contributes to the neddylation of all cullins by transfering NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which is necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs). May play a role in DNA damage response and may participate to cell proliferation and anchorage-independent cell growth.[UniProtKB/Swiss-Prot Function]

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