Mouse Kdm4c activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kdm4c
Locus ID	76804
Kit Components	GA210620G1, Kdm4c gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210620G2, Kdm4c gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210620G3, Kdm4c gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001172095, NM_144787, NM_001356561
Synonyms	2410141F18Rik; AA517467; Gasc1; Jmjd2c
Summary	Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).[UniProtKB/Swiss-Prot Function]

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