Mouse Hectd3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hectd3
Locus ID	76608
Kit Components	GA210552G1, Hectd3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210552G2, Hectd3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210552G3, Hectd3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175244
Synonyms	1700064K09Rik; AI467540; AW743312
Summary	E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP (By similarity). Mediates also ubiquitination of STX8.[UniProtKB/Swiss-Prot Function]

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