Mouse Erp44 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Erp44
Locus ID	76299
Kit Components	GA210476G1, Erp44 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210476G2, Erp44 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210476G3, Erp44 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029572, NM_001355184
Synonyms	1110001E24Rik; AI849526; AL033348; Txndc4
Summary	Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum (By similarity).[UniProtKB/Swiss-Prot Function]

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