Mouse Agbl3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Agbl3
Locus ID	76223
Kit Components	GA210462G1, Agbl3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210462G2, Agbl3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210462G3, Agbl3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289656, NM_001289657, NM_001289658, NM_178630
Synonyms	2900053G10Rik; 4930431N21Rik; 6530406M24Rik; CCP3
Summary	Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin.[UniProtKB/Swiss-Prot Function]

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