Mouse Dock11 activation kit by CRISPRa
CAT#: GA210412
Dock11 CRISPRa kit - CRISPR gene activation of mouse dedicator of cytokinesis 11
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Dock11 |
Locus ID | 75974 |
Kit Components | GA210412G1, Dock11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210412G2, Dock11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210412G3, Dock11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001009947, NM_177745 |
Synonyms | 5033414A21Rik; 8030476J24; sph238; Zizimin2 |
Summary | Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP (PubMed:15710388, PubMed:16968698, PubMed:25851601). Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology (PubMed:25729399). Facilitates filopodia formation through the activation of CDC42 (PubMed:22494997).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN504736 | Dock11 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |