Mouse Zdhhc20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zdhhc20
Locus ID	75965
Kit Components	GA210411G1, Zdhhc20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210411G2, Zdhhc20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210411G3, Zdhhc20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029492, NM_001360097, NM_001360098
Synonyms	4930542A17Rik; 5033406L14Rik; AI448102; B230110O18Rik; ENSMUSG00000055956; HK11
Summary	Catalyzes palmitoylation of Cys residues on target proteins (PubMed:15603741). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation. Has a preference for acyl-CoA with C16 fatty acid chains. Can also utilize acyl-CoA with C14 and C18 fatty acid chains (By similarity).[UniProtKB/Swiss-Prot Function]

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