Mouse Vmp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Vmp1
Locus ID	75909
Kit Components	GA210397G1, Vmp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210397G2, Vmp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210397G3, Vmp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029478, NM_001356531
Synonyms	3110098I04Rik; 4930579A11Rik; AI787464; mir-21a; ni-2; Tango5; Tmem49
Summary	Stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death (By similarity). May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis (PubMed:17940279). Involved in cell-cell adhesion. Plays an essential role in formation of cell junctions. Plays a role in the initial stages of the autophagic process through its interaction with BECN1. Required for autophagosome formation (By similarity).[UniProtKB/Swiss-Prot Function]

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