Mouse Klf17 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Klf17
Locus ID	75753
Kit Components	GA210336G1, Klf17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210336G2, Klf17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210336G3, Klf17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029416
Synonyms	7420700M05Rik; AA420409; AU043468; C85123; D4Ertd561e; Gzf; Zfp393
Summary	Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.[UniProtKB/Swiss-Prot Function]

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