Mouse Wdr54 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Wdr54
Locus ID	75659
Kit Components	GA210301G1, Wdr54 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210301G2, Wdr54 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210301G3, Wdr54 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_023790, NM_001362119, NM_001362120
Synonyms	1700030E05Rik
Summary	When cross-linked to form dimers and trimers, it has a regulatory effect on ERK signaling pathway activity in response to EGF stimulation. Colocalizes with the EGF receptor in WDR54-specific vesicle where it sustains the internalization and controls the degradation of the EGF receptor after EGF stimulation.[UniProtKB/Swiss-Prot Function]

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