Mouse Atf7ip2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atf7ip2
Locus ID	75329
Kit Components	GA210176G1, Atf7ip2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210176G2, Atf7ip2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210176G3, Atf7ip2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029253, NM_153123
Synonyms	4930558K11Rik; BC018510; Get-1; PSM2
Summary	Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (By similarity).[UniProtKB/Swiss-Prot Function]

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