Mouse Rnf19b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rnf19b
Locus ID	75234
Kit Components	GA210136G1, Rnf19b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA210136G2, Rnf19b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA210136G3, Rnf19b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029219, NM_001368763
Synonyms	4930534K13Rik; 4930555L03Rik; Ibrdc3
Summary	E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. Protects against staurosporin-induced cell death (By similarity).[UniProtKB/Swiss-Prot Function]

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