Mouse Osbpl10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Osbpl10
Locus ID	74486
Kit Components	GA209914G1, Osbpl10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209914G2, Osbpl10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209914G3, Osbpl10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_148958, NM_176901
Synonyms	4933433D06Rik; C820004B04Rik; OPR-10; ORP-10
Summary	Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate (PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P. Plays a role in negative regulation of lipid biosynthesis. Negatively regulates APOB secretion from hepatocytes. Binds cholesterol and acidic phospholipids. Also binds 25-hydroxycholesterol. Binds phosphatidylserine.[UniProtKB/Swiss-Prot Function]

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