Mouse Pus10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pus10
Locus ID	74467
Kit Components	GA209901G1, Pus10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209901G2, Pus10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209901G3, Pus10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001033654, NM_028304, NM_028956
Synonyms	2810013G11Rik; 4933435A13Rik; AU014648; C77560; Ccdc139
Summary	Pseudouridylate synthases catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death (By similarity).[UniProtKB/Swiss-Prot Function]

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