Mouse Rmi1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rmi1
Locus ID	74386
Kit Components	GA209861G1, Rmi1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209861G2, Rmi1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209861G3, Rmi1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001168248, NM_028904, NR_031761
Synonyms	4932432N11Rik; C79893
Summary	Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability (By similarity).[UniProtKB/Swiss-Prot Function]

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