Mouse Slc6a19 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc6a19
Locus ID	74338
Kit Components	GA209837G1, Slc6a19 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA209837G2, Slc6a19 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA209837G3, Slc6a19 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028878, NM_001359603
Synonyms	4632401C08Rik; B<0>AT1
Summary	Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells (PubMed:17167413, PubMed:26240152, PubMed:19185582, PubMed:15044460). Required CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity (PubMed:19185582, PubMed:17167413). This uptake is sodium-dependent and chloride-independent (PubMed:15044460, PubMed:18424768, PubMed:19185582, PubMed:21636576, PubMed:26240152).[UniProtKB/Swiss-Prot Function]

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